# Why disorder changes drug discovery

> Why intrinsically disordered proteins require discovery methods that measure populations, model motion, and test transient pockets.

[View this page on Peptone](https://peptone.io/blog/2026-05-idp-drug-discovery/)

Published: 2026-05-01

Author: Peptone

Intrinsically disordered proteins require a discovery workflow that can measure ensembles, model motion, and test binders against transient pockets.