Peptone sponsors Gordon Research Conference 2024 on Biophysics and Biology of Intrinsically Disordered Proteins

Peptone team will attend the annual Gordon Research Conference 2024 on Biophysics and Biology of Intrinsically Disordered Proteins in Les Diablerets, Vaud, Switzerland.

Join our team at GRC

We are thrilled to announce that our Chief Scientific Officer, Dr. Patrik Foerch, and our Principal Scientist, Dr. Sandro Bottaro, will participate in the annual 2024 Gordon Research Conference on the Biophysics and Biology of Intrinsically Disordered Proteins.

About the conference

The Intrinsically Disordered Proteins GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

Intrinsically disordered proteins (IDPs), as opposed to intrinsically foldable proteins, do not adopt unique folded structures but instead exist as ensembles of dynamic and unstructured interconverting conformations. IDPs and ID regions function through these conformational ensembles and are drivers of biological outputs. The conformations of IDPs are a direct consequence of their sequences, physicochemical properties, and the environment in which they reside. IDPs come in many different flavors, exemplified by sequence features such as amino acid composition and patterning, and they can exist in the context of multi-domain proteins and in different environmental contexts. Combined, this determines their functions and mechanisms of action in different cells and organisms. Sequences can also encode material properties that emerge when many molecules come together in large assemblies, and this is important in biological function as well as for biomaterial science. Understanding how the sequence grammar and the precise context give rise to conformations and functions, from single molecules to assemblies, on time scales from picoseconds to years, is important for elucidating how IDPs shape biology and how their dysregulation gives rise to diseases.

About Peptone

Peptone is a translational biophysics company focused on the discovery of novel therapeutics against diseases driven by intrinsically disordered proteins. IDPs are proteins without a fixed structure that play a significant role in health and disease.